Can't Install or Run Programs (EXEs) From ANY External Drive

[DanTheTechMan]

Hi. I have a very strange issue.  I just upgraded to the newest release of Windows 10 (Redstone), and now, I can't run anything off my external hard drive.  I believe it has something to do with UAC, because after I disabled it, I could run the software from my external, however, none of the built in Microsoft apps would run, as Windows thought I was using the built-in Administrator account (this would only happen with UAC disabled). With UAC enabled, I would get an access denied error.  So, I'm at the point where I have to choose between the built in Microsoft apps or the ability to run installers form my external hard drive, however I shouldn't have to choose.  I Should be able to access everything on my PC, without any issues.  I've already tried playing with the drive permissions, to no avail.  Does anyone have any other ideas on how to remedy this?

[DanTheTechMan]

So, almost a month, and no replies? I'm still facing this issue, but to give you a better understanding, it's just with executable files (.exe) and this happens on any drive EXCEPT the one that Windows is installed on.  This is a real pain, because I keep all my installers on an external (separate from the OS) and in order to install something, I have to copy it to the OS drive, then run the installer, which can get to be really annoying for large files or anything off a a disc or removable media (such as a flash drive or SD card).  With this new (clarified) information, is there anyone out there that can shed some light on this now?