Can you boot up into Safe Mode with Networking, open Windows Repair - go to Backup Tools and use the Registry Restore option.
Click on the Registry Restore tab and use the dropdown to select the back up then click on Restore Now.
Boot back into Safe Mode with Networking and download and create a Kaspersky Rescue disk.
https://support.kaspersky.co.uk/viruses/rescuediskYou will need to change the boot order to boot up with this disk and while your system boots up, it may be prudent to run it to check that you are infection free.
The scan can take a while to complete.
It can also correct Windows anomalies.
You will need to be connected to the Internet when you run this disk as it needs to update its Definitions.
Does Explorer still crash in Safe Mode ?
Black screening is usually indicative of memory problems but given that an open program will still run would eliminate that as a cause this time, but doing a memory diagnostic check wouldn't harm anyway.
Do I assume you are running Win 10 ?
After restoring the registry I would normally advise a repair install but that could be problematic if Explorer is crashing.
Depending upon which version of Windows you are running, the next best thing if running Win 10 would be to back up your personal stuff onto external media and then boot up to the advanced boot options and use the Reset option that retains your personal stuff but will remove any 3rd party programs you have installed.