That would confirm it was related to an antivirus program as Shane has found -
https://forum.kaspersky.com/index.php?showtopic=362231AV programs aren't loaded in Safe Mode.
You only need to post the CBS log if sfc /scannow reported it was unable to repair all files.
It sounds like your hard drive is a bit full.
You haven't said which version of Windows you are using.
If Win 7 then go Start - type disk cleanup - right click on Disk Cleanup and select Run as administrator.
If later than Win 7 - go Start - type disk cleanup and press enter.
When it has done its scan, click on Clean System files where it should find a lot more to remove.
You can gain some more space on your hard drive by turning Hibernate off.
For Win 7 go Start - type cmd - right click on cmd and select Run as administrator and accept the UAC.
For later, Open a Command Prompt (Admin) - accept the UAC then enter powercfg -h off - that frees up about 6GB for me.
Check to see if you have 15% of the total hard drive free and then you can run a defrag from the admin command prompt by entering defrag /c
This will analyze and defrag all volumes as necessary.
If you still don't have a min of 15% free then you are going to have to copy large files such as photos etc onto an external HDD of sufficient capacity - but I'd do that anyway as Virtual Memory relies on free space on the hard drive.