I just know the speeds of the device what the page file runs on is what is important.
On a external hard drive hooked to a usb 2.0 the max speed the drive can go is 25 MB/s through usb 2.0
On usb 3.0 that external hard drive can go full speed. Good to know when doing big backups
Thumb drives are even slower. I would have the page file run on the fastest possible drive, try reading data and writing to a 2gb file on a slow device. While most of the file may be empty and normally on a good system with no memory leaks Windows may only be writing 20 to 50 mb worth of memory to it that is still at the mercy of the speed of the drive.
How ready boost makes anything faster I dont really know lol because with a heavily used page file it would slow to a crawl.
So for my own personal reasons I found it FAR faster and more stable not having a page file enabled. So for you I say try and test and find what you like and do what you want.
You are not going to hurt anything by doing it and you can get an idea of how things feel.
Shane